Search results for " insight"
showing 10 items of 19 documents
Biodiversity change after climate-induced ice-shelf collapse in the Antarctic
2011
Julian Gutt ... et al. -- 10 pages, 5 figures, 1 table, supplementary data https://doi.org/10.1016/j.dsr2.2010.05.024
Resting-state posterior alpha rhythms are abnormal in subjective memory complaint seniors with preclinical Alzheimer's neuropathology and high educat…
2020
International audience; Cognitive reserve is present in Alzheimer's disease (AD) seniors with high education attainment making them clinically resilient to extended brain neuropathology and neurodegeneration. Here, we tested whether subjective memory complaint (SMC) seniors with AD neuropathology and high education attainment of the prospective INSIGHT-preAD cohort (Paris) may present abnormal eyesclosed resting state posterior electroencephalographic rhythms around individual alpha frequency peak, typically altered in AD patients. The SMC participants negative to amyloid PET AD markers (SMCneg) with high (over low-moderate) education level showed higher posterior alpha 2 power density (pos…
Microcephaly/Trigonocephaly, Intellectual Disability, Autism Spectrum Disorder, and Atypical Dysmorphic Features in a Boy with Xp22.31 Duplication
2019
The Xp22.31 segment of the short arm of the human X chromosome is a region of high instability with frequent rearrangement. The duplication of this region has been found in healthy people as well as in individuals with varying degrees of neurological impairment. The incidence has been reported in a range of 0.4-0.44% of the patients with neurological impairment. Moreover, there is evidence that Xp22.31 duplication may cause a common phenotype including developmental delay, intellectual disability, feeding difficulty, autistic spectrum disorders, hypotonia, seizures, and talipes. We report on a patient with microcephaly and trigonocephaly, moderate intellectual disability, speech and languag…
Quality of Life in Dementia: Impact of Cognition and Insight on Applicability of the SF-36
2011
Comparability of measures of quality of life in dementia and in other diagnostic groups, such as mild cognitive impairment, normal aging, or other diseases, is highly desirable. However, the impact of cognitive deficits and impaired insight on applicability and validity of generic instruments is sparsely studied.Sixty patients with dementia [38 women; age: mean (SD) = 78.7 (6.4) years; Mini-Mental State Examination (MMSE): mean (SD) = 20.2 (6.0)] recruited as part of the start-modem study, a multicenter care research study in Germany, completed the generic instrument SF-36 and the specific instrument Quality of Life-Alzheimer's Disease (QOL-AD).QOL-AD self-rating scores [mean (SD) = 32.8 (5…
Telia Crowd Insights -tietojen hyödyntäminen pandemiatietoisuuden parantamiseksi Keski-Suomessa
2021
Telia Crowd Insights -tietojen hyödyntäminen pandemiatietoisuuden parantamiseksi KeskiSuomessa on Keski-Suomen liiton rahoittama hanke, jolla pyritään selvittämään, että pystytäänkö ihmisten ja ihmisvirtojen liikkeitä seuraamalla saavuttamaan parempi tilannekuva pandemia tilanteessa. Hankkeen tarkoituksena on keskittyä erilaisiin liikenteenseurantaratkaisuihin sekä tutkia koronaviruksen aiheuttamia vaikutuksia maakunnassa tapahtuvaan liikenteeseen ja liikkumiseen. Keväällä 2020 tuli voimaan poikkeukselliset olosuhteet, joiden takia liikenne muuttui merkittävästi erilaisten rajoitusten ja yleisen varovaisuuden vuoksi. Tämä on yksi merkittävimmistä ilmiöistä, joita projektissa pyritään tutkim…
Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation.
2014
Exosomes are small membranous vesicles of endocytic origin that are released by almost every cell type. They exert versatile functions in intercellular communication important for many physiological and pathological processes. Recently, exosomes attracted interest with regard to their role in cell–cell communication in the nervous system. We have shown that exosomes released from oligodendrocytes upon stimulation with the neurotransmitter glutamate are internalized by neurons and enhance the neuronal stress tolerance. Here, we demonstrate that oligodendroglial exosomes also promote neuronal survival during oxygen–glucose deprivation, a model of cerebral ischaemia. We show the transfer from…
The 15 March 2007 explosive crisis at Stromboli Volcano, Italy: assessing physical parameters through a multidisciplinary approach
2011
Basaltic volcanoes are dominated by lava emission and mild explosive activity. Nevertheless, many basaltic systems exhibit, from time to time, poorly documented and little-understood violent explosions. A short-lived, multiblast explosive crisis (paroxysmal explosion) occurred on 15 March 2007 during an effusive eruptive crisis at Stromboli (Italy). The explosive crisis, which started at 20:38:14 UT, had a total duration of ∼5 min. The combined use of multiparametric data collected by the permanent instrumental networks (seismic, acoustic, and thermal records) and a field survey carried out immediately after the event enabled us to constrain the eruptive dynamics and quantify physical param…
Novel clinical insights into spinal hemangioblastoma in adults: a systematic review
2021
ABSTRACT Background Hemangioblastomas are well vascularized, benign CNS tumors and the third most common primary spinal cord tumor after astrocytoma/ependymoma, occurring sporadically or as a part of an autosomal dominant von Hippel-Lindau disease in which tumors are often multiple and prone to relapse. Spinal hemangioblastomas are commonly located in the cervical cord and associated with a syrinx formation. Due to location and growth trends, they may cause significant neurological deficit, impairing patient quality of life. We conducted a systematic review to understand better clinical insights of spinal hemangioblastoma in adults and compare spinal hemangioblastoma versus posterior crania…
Lessons from the 2018-2019 European droughts : a collective need for unifying drought risk management
2022
Funding Information: This open-access publication was funded by the University of Freiburg. Funding Information: Financial support. The project is supported by the Wassernetzwerk Baden-Württemberg (Water Research Network of the State Baden-Württemberg), which is funded by the Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg (Ministry of Science, Research and the Arts of the State Baden-Württemberg) (grant no. AZ. 7532.21/2.1.6) and Maa-ja vesitekniikan tuki ry foundation. Doris E. Wendt acknowledges her support as part of the NERC-funded Groundwater Drought Initiative (NE/R004994/1). Lucy J. Barker was supported by the Natural Environment Research Council (NE/R016429/1) a…
The young Ramón y Cajal as a cell-theory dissenter
2008
Pereto Magraner, Juli, Juli.Pereto@uv.es